Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses [Biophysics and Computational Biology],Proceedings of the National Academy of Sciences of the United States of America

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Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses [Biophysics and Computational Biology]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-03-24
Jae-Hyun Cho, Baoyu Zhao, Jie Shi, Nowlan Savage, Qingliang Shen, James Byrnes, Lin Yang, Wonmuk Hwang, Pingwei Li

The 1918 influenza A virus (IAV) caused the most severe flu pandemic in recorded human history. Nonstructural protein 1 (NS1) is an important virulence factor of the 1918 IAV. NS1 antagonizes host defense mechanisms through interactions with multiple host factors. One pathway by which NS1 increases virulence is through the...

中文翻译：

大流行性和季节性甲型流感病毒的NS1对宿主蛋白的分子识别[生物物理学和计算生物学]

1918年的甲型流感病毒（IAV）在人类历史记录中引起了最严重的流感大流行。非结构蛋白1（NS1）是1918 IAV的重要毒力因子。NS1通过与多种宿主因素的相互作用来拮抗宿主防御机制。NS1增加毒性的一种途径是通过...

更新日期：2020-03-26

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