Background

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder. Previous studies have yielded divergent results on the prevalence of depression and anxiety in patients with HS.

Objective

The aim of this meta-analysis was to provide a pooled estimate of the prevalence and odds of depression/anxiety in patients with HS.

Methods

Search for and extraction of relevant literature without restrictions from 5 databases (Cochrane Database, EMBASE, PubMed, PsycINFO, Science Direct) were performed. Pooled meta-analyses were made by using random-effects models.

Results

Meta-analyses of 28 studies of depression in HS and 12 of anxiety showed a prevalence of 21% (95% CI [17-25]) of depression and 12% (95% CI [6-17]) of anxiety in patients with HS, with very wide variations in both cases. Analysis of case-control studies showed an association between depression and HS (odds ratio, 1.99 95% CI [1.63-2.43]) and between anxiety and HS (odds ratio, 1.97 95% CI [1.65-2.35]).

Limitations

The results of this meta-analysis are conditioned by the limitations of the studies included and by differences in patient populations, methodologic approach, and data available.

Conclusion

Patients with HS have a high burden of depression and anxiety. Our results show that clinicians need to be vigilant for the presence of depression or anxiety and to refer patients when appropriate.

中文翻译：

---

儿童和成人化脓性汗腺炎的焦虑和抑郁的患病率和患病率：系统评价和荟萃分析。

背景

化脓性汗腺炎（HS）是一种慢性炎症性皮肤病。先前的研究对HS患者的抑郁和焦虑患病率产生了分歧的结果。

目的

这项荟萃分析的目的是提供HS患者抑郁/焦虑患病率和患病几率的汇总估算。

方法

从5个数据库（Cochrane数据库，EMBASE，PubMed，PsycINFO，Science Direct）中无限制地搜索和提取相关文献。通过使用随机效应模型进行汇总荟萃分析。

结果

对28例HS抑郁症和12例焦虑症进行的荟萃分析显示，合并症患者的抑郁症患病率为21％（95％CI [17-25]），焦虑症患病率为12％（95％CI [6-17]） HS，在两种情况下差异很大。病例对照研究的分析表明，抑郁与HS之间的关联（优势比，1.99 95％CI [1.63-2.43]）和焦虑与HS之间的关联（优势比，1.97 95％CI [1.65-2.35]）。

局限性

这项荟萃分析的结果取决于所研究的局限性以及患者人群，方法学方法和可用数据的差异。

结论

HS患者的抑郁和焦虑负担很高。我们的结果表明，临床医生需要对是否存在抑郁或焦虑保持警惕，并在适当时转诊患者。