The recent paper from Sepriano et al provides an extremely important new insight on the concept of axial spondyloarthritis (axSpA).1 Clearly, the Gestalt of axSpA is heterogeneous, with three recognisable clinical entities labelled as: ‘pure axial SpA’, ‘axial SpA with peripheral signs’ and ‘axial SpA at risk’. The finding given in the paper suggests a larger overlap between axSpA and pSpA than anticipated at the time when the Assessment of SpondyloArthritis international Society (ASAS) criteria were developed. Thus, the question arises as to how accurately the three recognisable clinical entities of the ASAS classification criteria represent the diseases entities originally lumped together in the historical concept of SpA. The unifying historical concept of SpA lumps together an inter-related yet heterogeneous group of disorders which includes ankylosing spondylitis …

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反应性关节炎，一个缺失的环节：评论 Sepriano 等人最近的文章

Sepriano 等人最近的论文提供了关于轴性脊柱关节炎 (axSpA) 概念的极其重要的新见解。 1 显然，axSpA 的格式塔是异质的，三个可识别的临床实体被标记为：“纯轴性 SpA”、“轴性 SpA”有外围体征”和“处于危险中的轴向 SpA”。论文中给出的发现表明 axSpA 和 pSpA 之间的重叠比制定国际脊柱关节炎评估协会 (ASAS) 标准时的预期要大。因此，问题在于 ASAS 分类标准的三个可识别的临床实体如何准确地代表最初在 SpA 的历史概念中归为一类的疾病实体。