Efficient and Uncatalyzed Synthesis of Highly Functionalized New Symmetrical Indeno[1,2‐b]pyrroles via a One‐Pot Four‐Component Reaction,ChemistrySelect

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Efficient and Uncatalyzed Synthesis of Highly Functionalized New Symmetrical Indeno[1,2‐b]pyrroles via a One‐Pot Four‐Component Reaction
ChemistrySelect ( IF 1.9 ) Pub Date : 2020-03-24 , DOI: 10.1002/slct.201904860
Atieh Rezvanian ₁ , Fahame Mahmoodi ₁ , Vahideh Zadsirjan ₁ , Mehri Salimi ₁ , Majid M. Heravi ₁

Affiliation

A facile, efficient and un‐catalyzed approach for the synthesis of new symmetrical highly‐ substituted indeno [1,2‐b]pyrrole derivatives through four‐component reaction, involving, primary amines, diamine, diketene, and ninhydrin in CH₂Cl₂ at ambient temperature is reported. This approach enjoys merits such as being done in the absence of catalyst at ambient temperature, giving good to excellent yields, completed in short reaction times, and showing a wide functional group tolerance.

中文翻译：

通过一锅四组分反应高效且无催化地合成高度官能化的新型对称[1,2-b]吡咯

一种通过四组分反应合成新的对称性高取代度茚并[1,2- b ]吡咯衍生物的简便，高效且未催化的方法，其中涉及CH ₂ Cl _2中的伯胺，二胺，双烯酮和茚三酮报告在环境温度下。该方法具有诸如在环境温度下不存在催化剂的情况下进行的优点，良好的优异收率，在短的反应时间内完成并且显示出宽的官能团耐受性。

更新日期：2020-03-24

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