当前位置: X-MOL 学术Cancer › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Searching for the perfect combination of drug, disease, genetic alteration, and screening test to maximize FGFR inhibition in urothelial cancer.
Cancer ( IF 6.2 ) Pub Date : 2020-03-24 , DOI: 10.1002/cncr.32804
Chelsea K Osterman 1 , Matthew I Milowsky 1, 2
Affiliation  

New targeted therapies to inhibit fibroblast growth factor receptor (FGFR) represent a promising treatment option for patients with metastatic urothelial carcinoma (mUC). Despite significant advances, the optimal combination of drug, disease, genetic alteration, and screening test that together lead to maximal efficacy of FGFR inhibition for patients with mUC remains to be determined.

中文翻译:

寻找药物,疾病,基因改变和筛选测试的最佳组合,以最大程度地抑制尿路上皮癌中的FGFR抑制作用。

抑制成纤维细胞生长因子受体(FGFR)的新靶向疗法代表了转移性尿路上皮癌(mUC)患者的有前途的治疗选择。尽管取得了重大进展,但尚需确定药物,疾病,基因改变和筛选试验的最佳组合,以共同抑制mUC患者的FGFR发挥最大功效。
更新日期:2020-03-24
down
wechat
bug