We contrive two strategies to assemble well-defined nanoclusters with high-throughput guided by DNA origami frames either by (1) introducing a micro-sized surface to fabricate patchy particles for binding with DNA structures or (2) restricting the assembly process of free nanoparticles and DNA origami frames on the fixed sites. Both the strategies can omit the process of gel purification of the final products.

中文翻译：

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由高通量DNA折纸框架引导的纳米簇的逐步组装。

我们设计了两种策略来组装清晰定义的纳米簇，这些簇由DNA折纸框架引导，方法是：（1）引入一个微尺寸的表面来制造与DNA结构结合的斑驳颗粒，或者（2）限制自由纳米颗粒的组装过程固定位置上的DNA折纸框架。两种策略都可以省略最终产物的凝胶纯化过程。