Different populations of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) from Central Africa are susceptible to Zika virus infection.,PLOS Neglected Tropical Diseases

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Different populations of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) from Central Africa are susceptible to Zika virus infection.
PLOS Neglected Tropical Diseases ( IF 3.4 ) Pub Date : 2020-03-23 , DOI: 10.1371/journal.pntd.0008163
Basile Kamgang ₁ , Marie Vazeille ₂ , Armel Tedjou _{1,

3} , Aurélie P Yougang _{1,

3} , Theodel A Wilson-Bahun _{1,

4} , Laurence Mousson ₂ , Charles S Wondji _{1,

5} , Anna-Bella Failloux ₂

Affiliation

Zika virus (ZIKV) is a Flavivirus (Flaviviridae) transmitted to humans mainly by the bite of an infected Aedes mosquitoes. Aedes aegypti is the primary epidemic vector of ZIKV and Ae. albopictus, the secondary one. However, the epidemiological role of both Aedes species in Central Africa where Ae. albopictus was recently introduced is poorly characterized. Field-collected strains of Ae. aegypti and Ae. albopictus from different ecological settings in Central Africa were experimentally infected with a ZIKV strain isolated in West Africa. Mosquitoes were analysed at 14- and 21-days post-exposure. Both Ae. aegypti and Ae. albopictus were able to transmit ZIKV but with higher overall transmission efficiency for Ae. aegypti (57.9%) compared to Ae. albopictus (41.5%). In addition, disseminated infection and transmission rates for both Ae. aegypti and Ae. albopictus varied significantly according to the location where they were sampled from. We conclude that both Ae. aegypti and Ae. albopictus are able to transmit ZIKV and may intervene as active Zika vectors in Central Africa. These findings could contribute to a better understanding of the epidemiological transmission of ZIKV in Central Africa and develop suitable strategy to prevent major ZIKV outbreaks in this region.

中文翻译：

来自中非的不同种群的埃及伊蚊和白纹伊蚊（双翅目：Culicidae）易感染寨卡病毒。

寨卡病毒 (ZIKV) 是一种黄病毒 (Flaviviridae)，主要通过受感染的伊蚊叮咬传播给人类。埃及伊蚊是 ZIKV 和 Ae 的主要流行病媒介。albopictus，第二个。然而，这两种伊蚊在中非的流行病学作用。albopictus 最近引入的特征很差。现场收集的 Ae 菌株。埃及和 Ae。来自中非不同生态环境的白纹菌被西非分离的 ZIKV 毒株实验性感染。在暴露后 14 天和 21 天对蚊子进行分析。两个Ae。埃及和 Ae。albopictus 能够传播 ZIKV，但对 Ae 具有更高的整体传播效率。aegypti (57.9%) 与 Ae 相比。白纹病菌（41.5%）。此外，两种 Ae 的传播感染和传播率。埃及和 Ae。albopictus 根据采样地点的不同而有显着差异。我们得出结论，两者都是 Ae。埃及和 Ae。albopictus 能够传播 ZIKV，并可能作为活跃的 Zika 媒介在中非进行干预。这些发现有助于更好地了解 ZIKV 在中非的流行病学传播，并制定适当的策略来预防该地区的主要 ZIKV 爆发。

更新日期：2020-03-24

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