Lamin proteins not only form the nuclear lamina, but some are also found in the nuclear interior. In this issue of Developmental Cell, Ikegami et al. describe that phosphorylated Lamin C in the nuclear interior interacts with enhancer-like elements and link this to deregulated transcription in progeria.

中文翻译：

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常染色质中的磷酸化核纤层蛋白：早衰的新线索

层粘蛋白不仅形成核层，而且在核内部也发现了一些。在本期《发育细胞》中，池上等人。描述了核内的磷酸化Lamin C与增强子样元件相互作用，并将其与早衰症中转录失调有关。