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Sutterella Species, IgA-degrading Bacteria in Ulcerative Colitis.
Trends in Microbiology ( IF 15.9 ) Pub Date : 2020-03-23 , DOI: 10.1016/j.tim.2020.02.018
Nadeem O Kaakoush 1
Affiliation  

Recent reports link Sutterella with gastrointestinal diseases, the most intriguing being therapeutic failure in ulcerative colitis (UC). Sutterella does not appear to induce substantial inflammation; rather, it has a capacity to degrade IgA. This activity, however, is not conserved, presenting a key target to deciphering the influence of Sutterella on the host.



中文翻译:

Sutterella种,溃疡性结肠炎中降解IgA的细菌。

最近的报道将Sutterella与胃肠道疾病联系起来,最有趣的是溃疡性结肠炎(UC)的治疗失败。沙门氏菌似乎没有引起严重的炎症;相反,它具有降解IgA的能力。但是,这项活动并未得到保留,它是破解Sutterella对宿主的影响的关键目标。

更新日期:2020-03-23
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