当前位置:
X-MOL 学术
›
Trends Microbiol.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Sutterella Species, IgA-degrading Bacteria in Ulcerative Colitis.
Trends in Microbiology ( IF 14.0 ) Pub Date : 2020-03-23 , DOI: 10.1016/j.tim.2020.02.018 Nadeem O Kaakoush 1
中文翻译:
Sutterella种,溃疡性结肠炎中降解IgA的细菌。
更新日期:2020-03-23
Trends in Microbiology ( IF 14.0 ) Pub Date : 2020-03-23 , DOI: 10.1016/j.tim.2020.02.018 Nadeem O Kaakoush 1
Affiliation
Recent reports link Sutterella with gastrointestinal diseases, the most intriguing being therapeutic failure in ulcerative colitis (UC). Sutterella does not appear to induce substantial inflammation; rather, it has a capacity to degrade IgA. This activity, however, is not conserved, presenting a key target to deciphering the influence of Sutterella on the host.
中文翻译:
Sutterella种,溃疡性结肠炎中降解IgA的细菌。
最近的报道将Sutterella与胃肠道疾病联系起来,最有趣的是溃疡性结肠炎(UC)的治疗失败。沙门氏菌似乎没有引起严重的炎症;相反,它具有降解IgA的能力。但是,这项活动并未得到保留,它是破解Sutterella对宿主的影响的关键目标。