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CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis
Allergy ( IF 12.6 ) Pub Date : 2020-04-14 , DOI: 10.1111/all.14288
Yin Yao 1 , Nan Wang 1 , Cai-Ling Chen 1 , Li Pan 1 , Zhi-Chao Wang 1 , Joseph Yunis 2 , Zhi-An Chen 3 , Yu Zhang 4 , Si-Tao Hu 1 , Xiao-Yan Xu 5 , Rong-Fei Zhu 6 , Di Yu 3, 4 , Zheng Liu 1
Affiliation  

The contribution of B‐cell subsets and T‐B cell interaction to the pathogenesis of allergic rhinitis (AR) and mechanisms of allergen immunotherapy (AIT) remain poorly understood. This study aimed to outline circulating B‐cell signature, the underlying mechanism, and its association with clinical response to AIT in patients with AR.

中文翻译:

转换记忆 B 细胞上的 CD23 表达桥接过敏性鼻炎中的 TB 细胞相互作用

B 细胞亚群和 T-B 细胞相互作用对变应性鼻炎 (AR) 发病机制的贡献和变应原免疫治疗 (AIT) 的机制仍知之甚少。本研究旨在概述循环 B 细胞特征、潜在机制及其与 AR 患者对 AIT 临床反应的关联。
更新日期:2020-04-14
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