Dengue is one of the most dangerous vector-borne diseases transmitted by Aedes mosquitoes. The use of mosquito repellents to protect human hosts and insecticides to reduce the mosquito population is a crucial strategy to prevent the disease. Here, we reported larvicidal and repellent activities of Mentha arvensis L. essential oil against Aedes aegypti, the main vector of the disease. The essential oil was extracted by hydro-distillation from the aromatic plant grown in Vietnam. The yield was 0.67% based on the weight of fresh leaves. The essential oil was analyzed by gas chromatography-mass spectrometry (GC-MS). The main components were menthol (66.04%), menthyl acetate (22.19%), menthone (2.51%), and limonene (2.04%). Toxicity test on Aedes aegypti larvae showed that the median lethal concentrations, LC₅₀ and LC₉₀ were 78.1 ppm (part per million) and 125.7 ppm, respectively. Besides, the essential oil showed excellent repellency on Aedes aegypti mosquitoes. At 25%, 50%, and 100% concentration, the respective complete protection times (CPTs) were 45 min, 90 min, and 165 min. When adding 5% vanillin to the essential oil (25%), the complete protection time of the essential oil increased up to 120 min. In conclusion, the EO from Mentha arvensis L. has been shown to be a promising natural larvicide and repellent against Aedes aegypti mosquitoes.

中文翻译：

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薄荷（Mentha arvensis L.）精油对埃及伊蚊的杀幼虫和驱避活性

登革热是伊蚊传播的最危险的媒介传播疾病之一。使用驱蚊剂来保护人体宿主和使用杀虫剂来减少蚊子数量是预防该病的关键策略。在这里，我们报道了薄荷香薄荷油对该疾病的主要媒介埃及伊蚊的杀幼虫和驱避作用。通过水蒸馏从越南生长的芳香植物中提取精油。基于新鲜叶子的重量，产率为0.67％。通过气相色谱-质谱法（GC-MS）分析精油。主要成分为薄荷醇（66.04％），乙酸薄荷酯（22.19％），薄荷酮（2.51％）和li烯（2.04％）。毒性测试埃及伊蚊幼虫的平均致死浓度LC ₅₀和LC ₉₀分别为78.1 ppm（百万分之一）和125.7 ppm。此外，精油对埃及伊蚊具有极好的驱蚊性。在浓度为25％，50％和100％的情况下，相应的完全保护时间（CPT）为45分钟，90分钟和165分钟。当在香精油中添加5％香兰素（25％）时，香精油的完全保护时间增加到120分钟。总之，来自薄荷脑的EO已被证明是一种有前途的天然杀幼虫剂和抗埃及伊蚊的驱虫剂。