To evaluate the feasibility of a surgical technique using a sub-perfluoro-n-octane (PFO) injection of ocular viscoelastic device (OVD) to stabilize inverted internal limiting membrane (ILM) flap for the treatment of macular hole retinal detachment (MHRD). This study was a retrospective, consecutive, interventional case series. Patients who underwent MHRD surgery with sub-PFO injection of OVD to stabilize inverted ILM flap onto the macular hole (MH) were reviewed. The color fundus and optical coherence tomography (OCT) images were collected and evaluated. The best-corrected visual acuity (BCVA) before and after surgery were compared as the functional outcome. The study included 8 eyes of 8 consecutive patients (mean age: 61.8 ± 7.1 years; mean follow-up period: 9.0 ± 2.5 months). All eyes (100%) achieved successful MH closure; 7 eyes (87.5%) demonstrated complete retinal reattachment, and 1 eye (12.5%) had minimal residual subretinal fluid parafoveally. Of the 8 patients, 7 patients (87.5%) had achieved improvement in BCVA after the primary surgery, whereas 1 eye remained stable. The average BCVA before and after the surgery at the last visit improved from 20/843 (1.63 ± 0.48 logMAR) to 20/200 (1.00 ± 0.39 logMAR) (P = 0.016). Anatomically, near-normal foveal contour was noted in five (62.5%) eyes at the final follow-up. The use of sub-PFO injection of OVD in MHRD surgery could stabilize inverted ILM flaps, achieve good anatomical results and improve postoperative BCVA.

中文翻译：

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眼粘弹性装置的全氟正辛烷注射辅助倒置内膜限制瓣在黄斑裂孔视网膜脱离手术中的应用：一种新技术

为了评估外科手术技术的可行性，该技术使用全氟正辛烷（PFO）眼粘弹性装置（OVD）注射来稳定倒置内膜（ILM）皮瓣，以治疗黄斑裂孔视网膜脱离（MHRD）。这项研究是回顾性，连续性，介入性病例系列。回顾了接受MHRD手术并进行亚PFO OVD注射以将倒置ILM皮瓣稳定到黄斑裂孔（MH）的患者。收集并评估彩色眼底和光学相干断层扫描（OCT）图像。比较手术前后的最佳矫正视力（BCVA）作为功能结局。该研究包括8位连续患者的8眼（平均年龄：61.8±7.1岁；平均随访时间：9.0±2.5个月）。所有眼睛（100％）均成功完成了MH闭合；7眼（87。5％的患者显示出完全的视网膜重新附着，并且1只眼（12.5％）的视网膜中央凹旁残留少量的视网膜。在8例患者中，有7例（87.5％）在初次手术后BCVA有所改善，而1眼保持稳定。上次就诊前后的平均BCVA从20/843（1.63±0.48 logMAR）提高到20/200（1.00±0.39 logMAR）（P = 0.016）。在解剖上，最后一次随访发现五只眼（62.5％）的中央凹轮廓接近正常。在MHRD手术中使用OVD的PFO注射可以稳定ILM反转皮瓣，达到良好的解剖效果并改善术后BCVA。而1眼保持稳定。上次就诊前后的平均BCVA从20/843（1.63±0.48 logMAR）提高到20/200（1.00±0.39 logMAR）（P = 0.016）。在解剖上，最后一次随访发现五只眼（62.5％）的中央凹轮廓接近正常。在MHRD手术中使用OVD的PFO注射可以稳定ILM反转皮瓣，达到良好的解剖效果并改善术后BCVA。而1眼保持稳定。上次就诊前后的平均BCVA从20/843（1.63±0.48 logMAR）提高到20/200（1.00±0.39 logMAR）（P = 0.016）。在解剖上，在最后的随访中发现五只（62.5％）眼的中心凹轮廓接近正常。在MHRD手术中使用OVD的PFO注射可以稳定ILM反转皮瓣，达到良好的解剖效果并改善术后BCVA。