To test specific mono‐agonists to the glucagon‐like peptide‐1 receptor (GLP‐1R), glucagon receptor (GCGR) and glucose‐dependent insulinotropic peptide receptor (GIPR), individually and in combination, in a mouse model of diet‐induced non‐alcoholic steatohepatitis (NASH) and fibrosis in order to decipher the contribution of their activities and potential additive effects to improving systemic and hepatic metabolism.

中文翻译：

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肠抑素联合疗法可治疗非酒精性脂肪性肝炎。

在饮食诱导的小鼠模型中单独或组合测试胰高血糖素样肽1受体（GLP-1R），胰高血糖素受体（GCGR）和葡萄糖依赖性促胰岛素肽受体（GIPR）的特定单激动剂非酒精性脂肪性肝炎（NASH）和纤维化，以了解其活性的贡献和潜在的累加作用对改善全身和肝脏代谢的影响。