A diastereoselective palladium-catalyzed dearomative formal (4+2) cycloaddition between vinyl benzoxazinanones and 3-nitroindoles has been developed. This reaction provides a concise route to tetrahydro-5H-indolo[2,3-b]quinolines in excellent yield (up to 94%) and diastereoselectivity (up to >98:2), with versatile functional handles including vinyl, nitro, and free NH groups.

中文翻译：

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钯催化的乙烯基苯并恶嗪酮与 3-硝基吲哚的脱羧甲醛 (4+2) 环加成反应

已开发出乙烯基苯并恶嗪酮和 3-硝基吲哚之间的非对映选择性钯催化脱芳基 (4+2) 环加成反应。该反应以优异的收率（高达 94%）和非对映选择性（高达 >98:2）提供了获得四氢-5H-吲哚并[2,3-b]喹啉的简洁途径，具有多种功能性处理，包括乙烯基、硝基和游离 NH 基团。