A synthesis of fluorinated pyrimidines under mild conditions from amidine hydrochlorides and the recently described potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

中文翻译：

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由β-氟烯酸酯盐合成4-氨基-5-氟嘧啶和5-氨基-4-氟吡唑

开发了在温和条件下由am盐酸盐和最近描述的2-氰基-2-氟乙烯酸钾合成氟化嘧啶的方法。测试了广泛的基材范围，并获得了极佳的产量。可以证明由相同的氟化前体合成氟化氨基吡唑，但效率较低。