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Rapid viral diagnosis and ambulatory management of suspected COVID-19 cases presenting at the infectious diseases referral hospital in Marseille, France, - January 31st to March 1st, 2020: A respiratory virus snapshot.
Travel Medicine and Infectious Disease ( IF 12.0 ) Pub Date : 2020-03-20 , DOI: 10.1016/j.tmaid.2020.101632
Sophie Amrane 1 , Hervé Tissot-Dupont 1 , Barbara Doudier 2 , Carole Eldin 3 , Marie Hocquart 2 , Morgane Mailhe 2 , Pierre Dudouet 2 , Etienne Ormières 2 , Lucie Ailhaud 2 , Philippe Parola 3 , Jean-Christophe Lagier 1 , Philippe Brouqui 1 , Christine Zandotti 4 , Laetitia Ninove 4 , Léa Luciani 4 , Céline Boschi 2 , Bernard La Scola 1 , Didier Raoult 1 , Matthieu Million 1 , Philippe Colson 1 , Philippe Gautret 3
Affiliation  

Background

Rapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases.

Method

We managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. Rapid viral detection was performed on sputum and nasopharyngeal samples.

Results

Over our study period, no SARS-CoV-2 was detected. Results were obtained within approximately 3 h of the arrival of patient samples at the laboratory. Other viral infections were identified in 49% of the patients, with most common pathogens being influenza A and B viruses, rhinovirus, metapneumovirus and common coronaviruses, notably HKU1 and NL63.

Conclusion

Early recognition of COVID-19 is critical to isolate confirmed cases and prevent further transmission. Early rule-out of COVID-19 allows public health containment measures to be adjusted by reducing the time spent in isolation.



中文翻译:

2020年1月31日至3月1日在法国马赛传染病转诊医院就诊的可疑COVID-19病例的快速病毒诊断和门诊治疗:呼吸道病毒快照。

背景

需要快速的病毒学诊断以限制可疑COVID-19病例的分离时间。

方法

我们在法国马赛的传染病参考医院中,通过快速护理回路和病毒学诊断,处理了首批280名怀疑患有COVID-19的患者。对痰液和鼻咽样品进行快速病毒检测。

结果

在我们的研究期间,未检测到SARS-CoV-2。在患者样品到达实验室后约3小时内获得结果。在49%的患者中发现了其他病毒感染,最常见的病原体是甲型和乙型流感病毒,鼻病毒,间质肺病毒和常见的冠状病毒,尤其是HKU1和NL63。

结论

早期识别COVID-19对于隔离确诊病例和防止进一步传播至关重要。尽早排除COVID-19,可以通过减少隔离所花费的时间来调整公共卫生控制措施。

更新日期:2020-03-20
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