The toxicities of some chlorinated and brominated polycyclic aromatic hydrocarbons (X-PAHs) are higher than their corresponding parent PAHs. However, the identification and quantitation of X-PAHs in environment are still changeable and limitedly reported. To develop a robust method for routine analysis of X-PAHs in environmental samples, the determination of 34 X-PAHs was performed and compared using different instruments, including gas chromatography-mass spectrometry (GC-MS), gas chromatography-tandem mass spectrometry (GC-MS/MS) in both electron ionization (EI) and negative chemical ionization (NCI) modes, and comprehensive two-dimensional gas chromatograph-tandem mass spectrometer (GC × GC-MS/MS). GC-EI-MS/MS possessed the highest sensitivity with method detection limits of 2.00-40.0 and 2.00-20.0 pg/g dry weight (dw) for Cl-PAHs and Br-PAHs, respectively. This validated method was then applied to analyze X-PAHs in indoor dusts from a typical e-waste dismantling workshop, and the concentrations of Σ18Br-PAHs (8.80-399 ng/g dw) were higher than Σ16Cl-PAHs (7.91-137 ng/g dw). The toxicity equivalency quantities (TEQs) of Cl-PAHs at e-waste dismantling workshop and Br-PAHs at raw materials crushing workshop showed the highest values of 176 and 453 pg·TEQ/g, respectively. Cl-PAHs and Br-PAHs posed a potential health risk to workers through dust ingestion in workshops. Further attention should be payed to the formation mechanism of X-PAHs and the health risk.

中文翻译：

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电子废物拆解车间室内粉尘中氯和溴化多环芳烃的污染状况和人体暴露风险：GC-MS，GC-MS / MS和GC×GC-MS / MS测定方法的比较。

一些氯化和溴化多环芳烃（X-PAH）的毒性高于其相应的母体PAH。但是，环境中X-PAHs的鉴定和定量仍然是可变的，并且报道有限。为了开发一种可靠的常规分析环境样品中X-PAHs的方法，使用多种仪器进行了34种X-PAHs的测定并进行了比较，包括气相色谱-质谱（GC-MS），气相色谱-串联质谱（ GC-MS / MS）在电子电离（EI）和负化学电离（NCI）模式下，以及全面的二维气相色谱-串联质谱仪（GC×GC-MS / MS）。GC-EI-MS / MS具有最高的灵敏度，对于Cl-PAHs和Br-PAHs的方法检测限为2.00-40.0 pg / g干重（dw），分别。然后将这种经过验证的方法应用于典型的电子废物拆解车间的室内灰尘中的X-PAHs，其Σ18Br-PAHs（8.80-399 ng / g dw）的浓度高于Σ16Cl-PAHs（7.91-137 ng）。 / g dw）。电子废物分解车间的Cl-PAHs和原料破碎车间的Br-PAHs的毒性当量（TEQs）最高，分别为176 pg·TEQ / g和453 pg·TEQ / g。Cl-PAHs和Br-PAHs通过在车间内摄入粉尘对工人构成潜在的健康风险。X-PAHs的形成机理和健康风险应进一步关注。电子废物分解车间的Cl-PAHs和原料破碎车间的Br-PAHs的毒性当量（TEQs）最高，分别为176 pg·TEQ / g和453 pg·TEQ / g。Cl-PAHs和Br-PAHs通过在车间内摄入粉尘对工人构成潜在的健康风险。X-PAHs的形成机理和健康风险应进一步关注。电子废物分解车间的Cl-PAHs和原料破碎车间的Br-PAHs的毒性当量（TEQs）最高，分别为176 pg·TEQ / g和453 pg·TEQ / g。Cl-PAHs和Br-PAHs通过在车间内摄入粉尘对工人构成潜在的健康风险。X-PAHs的形成机理和健康风险应进一步关注。