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Enhanced control release of thyme essential oils from electrospun nanofiber/polyamidoamine dendritic polymer for antibacterial platforms
Polymers for Advanced Technologies ( IF 3.1 ) Pub Date : 2020-03-19 , DOI: 10.1002/pat.4899
Niluphar Kamrudi 1 , Somaye Akbari 1 , Mohammad Haghighat Kish 1
Affiliation  

The motive of the present investigation is to probe the role of polyamidoamine dendritic polymer (PAMAM) as a nano‐carrier function on the stepwise‐release rate of thyme oil (TEO) as natural extract with a superior antibacterial property. To represent quantitative and kinetic trends of release from nylon 6 electrospun fiber mats of TEO from mats, single‐sensor gas diagnosis device as an applicable diagnostic tool was tested in a distinct time sheet. All mats were characterized using scanning electron microscopy (SEM), Fourier‐transform infrared spectroscopy (FTIR), surface tension, contact angle, and antibacterial activity. As an outcome, PAMAM is major responsible for the pretending burst release due to the remarkable branches and cavities of PAMAM which encapsulate TEO. Noticeably, long‐term exposure of TEO was reached compared to the counterpart sample and a higher amount of PAMAM renders further functionality to protect guest molecules and not let them move easily in the atmosphere. It is realized that the essence release of mats with 2 and 10 wt% of PAMAM moieties last up to 9 and 12 days, respectively. Interestingly, all functionalized samples prevent the growth of Escherichia coli and Staphylococcus aureus bacteria and antibacterial value for samples with PAMAM surpassed 100% while decreased around 15 to 50% for mats without PAMAM over a 2‐week period. The results revealed that the functionalized samples were a promising fragrance delivery system with more effective antibacterial activity.

中文翻译:

从静电纺丝纳米纤维/聚酰胺胺树枝状聚合物中释放百里香精油以控制抗菌平台

本研究的目的是探讨聚酰胺酰胺树突状聚合物(PAMAM)作为纳米载体功能对百里香油(TEO)作为天然提取物具有优异抗菌性能的逐步释放率的作用。为了表示TEO尼龙6电纺纤维垫从垫子中释放的定量和动力学趋势,在不同的时间表中测试了单传感器气体诊断设备作为适用的诊断工具。使用扫描电子显微镜(SEM),傅立叶变换红外光谱(FTIR),表面张力,接触角和抗菌活性来表征所有垫子。结果,由于PAMAM封装了TEO的显着分支和孔洞,PAMAM主要负责假装释放。明显地,与对应的样品相比,TEO的长期暴露已经达到,并且更高数量的PAMAM可以提供进一步的功能来保护客体分子,而不会使它们在大气中轻松移动。已经认识到,具有2和10wt%的PAMAM部分的垫的本质释放分别持续长达9天和12天。有趣的是,所有功能化的样本都阻止了含PAMAM的样品的大肠杆菌金黄色葡萄球菌的细菌和抗菌价值超过100%,而不含PAMAM的垫子在2周内下降了约15%至50%。结果表明,功能化的样品是具有更有效的抗菌活性的有前途的香料输送系统。
更新日期:2020-03-19
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