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Changing the Course of Cancer Care With Greater Precision.
JAMA Oncology ( IF 22.5 ) Pub Date : 2020-05-01 , DOI: 10.1001/jamaoncol.2019.6843
S Yousuf Zafar 1 , Hanna K Sanoff 2, 3
Affiliation  

One of us recently received exciting molecular testing results: a patient’s newly diagnosed metastatic colorectal cancer expressed microsatellite instability, a predictive biomarker for immunotherapy. The patient fell into the minority of patients with metastatic colorectal cancer for whom precision oncology truly alters the natural history of disease, potentially prolonging survival by years. Providing biomarker-driven immunotherapy certainly exemplified the tenets of precision oncology.



中文翻译:

更加精确地改变癌症治疗的过程。

我们中的一个人最近获得了令人兴奋的分子测试结果:一名患者的新诊断的转移性结直肠癌表达了微卫星不稳定性,这是免疫疗法的预测性生物标志物。该患者属于少数转移性大肠癌患者,对于这些患者而言,精确的肿瘤学真正改变了疾病的自然病史,可能将其生存期延长数年。提供生物标记物驱动的免疫疗法无疑是精确肿瘤学的宗旨。

更新日期:2020-05-01
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