Three different microbalances were coated with aptamers with thiol termination designed to attach to the capsid proteins of the whole Zika virus. The first microbalance was a 5 MHz commercial AT-cut (QSense) quartz microbalance that showed 1 Hz/ng sensitivity with minimum detectable signal (MDS) of 1 ng. The second sensor was a 10 MHz AT-cut quartz sensor that was extracted from a communication filter. It had 10 Hz/ng sensitivity and MDS of 0.1 ng. The third sensor was a 433 MHz Lithium Niobate (LiNbO3) sensor that was also extracted from a communication filter. It had 370 Hz/ng sensitivity and 2.7 pg MDS. These studies verify binding of the aptamers to the sensor surface and the Zika virus. They also clearly show the advantage of using the LiNbO3 high frequency microbalance.

中文翻译：

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433 MHz 铌酸锂微量天平适体涂层全寨卡病毒传感器，灵敏度为 370 Hz/ng

三种不同的微量天平都涂有带有巯基末端的适体，设计用于附着在整个寨卡病毒的衣壳蛋白上。第一个微量天平是 5 MHz 商用 AT-cut (QSense) 石英微量天平，灵敏度为 1 Hz/ng，最小可检测信号 (MDS) 为 1 ng。第二个传感器是从通信滤波器中提取的 10 MHz AT-cut 石英传感器。它具有 10 Hz/ng 的灵敏度和 0.1 ng 的 MDS。第三个传感器是一个 433 MHz 的铌酸锂 (LiNbO3) 传感器，它也是从通信滤波器中提取的。它具有 370 Hz/ng 灵敏度和 2.7 pg MDS。这些研究验证了适体与传感器表面和寨卡病毒的结合。他们还清楚地展示了使用 LiNbO3 高频微量天平的优势。