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Display of Phosphorus-Containing Components on Low-Frequency Magnetic Resonance Images Using Double Magnetic Resonance
Applied Magnetic Resonance ( IF 1.1 ) Pub Date : 2019-12-02 , DOI: 10.1007/s00723-019-01174-0
Sergey Shubin , Viatcheslav Frolov , Konstantin Tyutyukin

One of the promising areas in MRI diagnostics is the mapping of the distribution of nuclei other than 1H. It is caused by the presence of such nuclei in molecules involved in important biological processes. The spatial distribution of these nuclei in a body can be judged on those or other pathological processes occurring in it. One of such nuclei is 31P, which plays an important role in a living organism. So, adenosine triphosphate is a main metabolite that plays a fundamental role as an energy transfer molecule and is involved in the construction of the cell membrane and in many other processes, for example, a phosphate donor and a signaling molecule inside the cells. This work presents the technique of displaying phosphorus-containing components in a ultralow magnetic field (7 mT) without a receiving signal of 31P using the double magnetic resonance method. The working substance in a phantom was the compound trimethyl phosphate (CH3O)3PO.

中文翻译:

使用双磁共振在低频磁共振图像上显示含磷成分

MRI 诊断中很有前景的领域之一是绘制 1H 以外的细胞核分布图。它是由参与重要生物过程的分子中存在此类核引起的。这些细胞核在体内的空间分布可以根据体内发生的那些或其他病理过程来判断。其中一种核是 31P,它在生物体中起着重要作用。因此,三磷酸腺苷是一种主要代谢物,作为能量转移分子发挥着重要作用,并参与细胞膜的构建和许多其他过程,例如磷酸供体和细胞内的信号分子。这项工作提出了使用双磁共振方法在没有 31P 接收信号的情况下在超低磁场 (7 mT) 中显示含磷成分的技术。体模中的工作物质是化合物磷酸三甲酯 (CH3O)3PO。
更新日期:2019-12-02
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