Abstract

The results of long-term author’s studies of the optical and complex-forming properties of more than 30 synthetic low-molecular-weight fluorophores specific for DNA are described. These studies made it possible to significantly expand the already existing database of properties of such compounds, clarify the ideas about the patterns linking the mentioned properties of fluorophores with their structure, and formulate recommendations on designing new effective DNA-specific fluorophores. The results of these studies can be used, in particular, in the development of new rapid methods for diagnosing various diseases, biotesting of probiotic and antibiotic properties of various products and wastes, etc.

中文翻译：

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荧光DNA探针：性质和应用方法的研究。

摘要

描述了长期作者对30多种对DNA特异的合成低分子量荧光团的光学和复合物形成特性的研究结果。这些研究使得有可能极大地扩展已经存在的这类化合物的性质的数据库，阐明有关将荧光团提及的性质与其结构联系起来的模式的想法，并就设计新的有效的DNA特异性荧光团提出建议。这些研究的结果可用于开发各种疾病的快速诊断方法，各种产品和废物的益生菌和抗生素特性的生物测试等。