BACKGROUND Diabetes mellitus (DM), has been associated with increased fracture risk. However, there are no data pertaining to the prevalence of fractures for patients with DM in India. The aim of this study was to determine the prevalence of fractures in Asian Indians with and without diabetes. METHODS The study used the data of Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study, a community- based cross sectional survey conceived with the aim of obtaining the prevalence rates of diabetes in India as a whole. A community-based sample of 57,117 individuals aged ≥20 years was obtained. Diabetes was diagnosed by oral glucose tolerance test using capillary blood (except in self-reported diabetes). Fractures were self-reported. RESULTS Fracture data were available in 54,093 subjects. Out of these, 1416 (2.6%) had fractures. Overall prevalence of diabetes and prediabetes was 7.1% and 10.5% respectively. Prevalence of fractures was significantly higher in diabetes group (4%) compared with non-diabetes group (2.5%). In multivariate logistic regression analysis, diabetes was associated with an increased risk (1) of any fracture (OR=1.28, 95% CI: 1.07-1.5) and (2) of low trauma fracture (hip and spine combined) (OR = 1.8, 95% CI:1.1-2.8). After gender stratification, diabetes was a risk factor for fracture only in women. Age (>40 years) in women, high waist circumference (>90 cm) in men, alcohol consumption and urban residence in both men and women were other significant contributors to fracture risk. CONCLUSION Increased prevalence of self-reported fractures was seen in individuals with diabetes in this population-based study from India.

中文翻译：

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亚洲印度糖尿病患者自我报告骨折的患病率增加：基于 ICMR-INDIAB 人群的横断面研究结果

背景糖尿病（DM）与骨折风险增加有关。然而，没有关于印度 DM 患者骨折患病率的数据。本研究的目的是确定患有和不患有糖尿病的亚洲印度人的骨折患病率。方法 该研究使用了印度医学研究理事会-印度糖尿病 (ICMR-INDIAB) 研究的数据，这是一项基于社区的横断面调查，旨在获得整个印度的糖尿病患病率。获得了 57,117 名年龄≥20 岁的基于社区的样本。糖尿病是通过使用毛细血管血进行口服葡萄糖耐量试验来诊断的（自我报告的糖尿病除外）。骨折是自我报告的。结果 54,093 名受试者的骨折数据可用。其中，1416 人（2.6%）有骨折。糖尿病和糖尿病前期的总体患病率分别为 7.1% 和 10.5%。与非糖尿病组 (2.5%) 相比，糖尿病组 (4%) 的骨折发生率显着更高。在多变量逻辑回归分析中，糖尿病与任何骨折（OR = 1.28，95% CI：1.07-1.5）和（2）低创伤骨折（髋部和脊柱合并）的风险增加（1）（OR = 1.8）相关, 95% 置信区间：1.1-2.8)。性别分层后，糖尿病仅是女性骨折的危险因素。女性年龄（> 40 岁）、男性腰围高（> 90 厘米）、男性和女性饮酒和城市居住是骨折风险的其他重要因素。结论 在这项来自印度的基于人群的研究中，发现糖尿病患者自我报告的骨折患病率增加。