In this issue of Molecular Cell, Gonatopoulos-Pournatzis et al. (2020) report a neuron-specific microexon in eIF4G translation initiation factors that dampens synaptic protein translation. Autism-associated disruption of this exon results in increased protein production, likely through reduced coalescence with cytoplasmic ribonucleoprotein granule components, including FMRP.

中文翻译：

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脑部翻译：羽毛提示体重秤。

在本期《分子细胞》中，Gonatopoulos-Pournatzis等人。（2020）报道了在eIF4G翻译起始因子中神经元特异性的微外显子，其抑制突触蛋白翻译。自闭症相关外显子的破坏导致蛋白质产生增加，可能是由于与胞质核糖核蛋白颗粒成分（包括FMRP）的结合减少。