Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic,Journal of the American College of Cardiology

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Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic
Journal of the American College of Cardiology ( IF 21.7 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.jacc.2020.03.031
Elissa Driggin ₁ , Mahesh V Madhavan ₂ , Behnood Bikdeli ₃ , Taylor Chuich ₁ , Justin Laracy ₁ , Giuseppe Biondi-Zoccai ₄ , Tyler S Brown ₅ , Caroline Der Nigoghossian ₁ , David A Zidar ₆ , Jennifer Haythe ₁ , Daniel Brodie ₁ , Joshua A Beckman ₇ , Ajay J Kirtane ₂ , Gregg W Stone ₈ , Harlan M Krumholz ₉ , Sahil A Parikh ₂

Affiliation

New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York.
New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York; Clinical Trials Center, Cardiovascular Research Foundation, New York, New York.
New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York; Clinical Trials Center, Cardiovascular Research Foundation, New York, New York; Center for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, Connecticut.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; Mediterranea Cardiocentro, Napoli, Italy.
Massachusetts General Hospital, Boston, Massachusetts.
Case Western Reserve School of Medicine, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio.
Vanderbilt University Medical Center, Nashville, Tennessee.
Clinical Trials Center, Cardiovascular Research Foundation, New York, New York; Icahn School of Medicine at Mount Sinai, New York, New York.
Center for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, Connecticut; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut; Department of Health Policy and Administration, Yale School of Public Health, New Haven, Connecticut.

Abstract The coronavirus disease-2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 that has significant implications for the cardiovascular care of patients. First, those with COVID-19 and preexisting cardiovascular disease (CVD) have an increased risk of severe disease and death. Second, infection has been associated with multiple direct and indirect cardiovascular complications including acute myocardial injury, myocarditis, arrhythmias and venous thromboembolism. Third, therapies under investigation for COVID-19 may have cardiovascular side effects. Fourth, the response to COVID-19 can compromise the rapid triage of non-COVID-19 patients with cardiovascular conditions. Finally, the provision of cardiovascular care may place health care workers in a position of vulnerability as they become host or vectors of virus transmission. We hereby review the peer-reviewed and preprint literature pertaining to cardiovascular considerations related to COVID-19 and highlight gaps in knowledge that require further study pertinent to patients, health care workers, and health systems.

中文翻译：

2019 年冠状病毒病 (COVID-19) 大流行期间患者、医护人员和卫生系统的心血管注意事项

摘要 2019 冠状病毒病（COVID-19）是一种由严重急性呼吸综合征冠状病毒 2 型引起的传染病，对患者的心血管护理具有重大影响。首先，患有 COVID-19 且既往患有心血管疾病 (CVD) 的患者患严重疾病和死亡的风险会增加。其次，感染与多种直接和间接心血管并发症有关，包括急性心肌损伤、心肌炎、心律失常和静脉血栓栓塞。第三，正在研究的 COVID-19 疗法可能会产生心血管副作用。第四，对 COVID-19 的反应可能会影响对患有心血管疾病的非 COVID-19 患者的快速分类。最后，提供心血管护理可能会使医护人员处于脆弱的境地，因为他们成为病毒传播的宿主或载体。我们特此回顾了与 COVID-19 相关的心血管注意事项的同行评审和预印本文献，并强调了需要进一步研究与患者、医护人员和卫生系统相关的知识差距。

更新日期：2020-05-01

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