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On the sylvatic transmission of T. cruzi, the parasite causing Chagas disease: a view from an agent-based model
Ecological Modelling ( IF 2.6 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.ecolmodel.2020.109001
N. El Saadi , A. Bah , T. Mahdjoub , C. Kribs

Abstract In this paper, we develop an agent-based model (ABM) to simulate the sylvatic transmission of the parasite T. cruzi, causative agent of Chagas disease (also called American trypanosomiasis). This ABM incorporates host-vector interactions, demographical processes for both hosts and vectors, and also vector and host dispersals. We implement the ABM under parameter values corresponding to real conditions in nature. The ABM simulations give quantitative results predicting the prevalence of the parasite T. cruzi in both hosts and vectors, the abundance of host and vector populations, and numerical estimates of the probability of persistence for T.cruzi population, depending on different initial spatial distributions of infection. Further, our study highlights the role of the host population as the determinant factor for infection transmission and parasite persistence, and presents pictures showing the emergence of clusters of infection.

中文翻译:

关于 T. cruzi 的森林传播,导致恰加斯病的寄生虫:基于代理模型的观点

摘要 在本文中,我们开发了一个基于代理的模型 (ABM) 来模拟寄生虫 T. cruzi 的森林传播,T. cruzi 是南美锥虫病(也称为美国锥虫病)的病原体。该 ABM 结合了宿主-媒介相互作用、宿主和媒介的人口统计过程,以及媒介和宿主的传播。我们在与自然界真实条件相对应的参数值下实现 ABM。ABM 模拟提供定量结果,预测寄主和载体中寄生虫 T. cruzi 的流行率、寄主和载体种群的丰度,以及 T.cruzi 种群持续概率的数值估计,取决于不同的初始空间分布感染。更多,
更新日期:2020-05-01
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