Bilateral diffuse uveal melanocytic proliferation (BDUMP) is an extremely rare paraneoplastic syndrome, with most cases reported as secondary to female urogenital and male lung malignancies. We reported this case of BDUMP patient whose primary malignancy was gastric adenocarcinoma verified with gastroscopy and subsequent pathological test. A patient complaining blurred vision was suspected of bilateral diffuse uveal melanocytic proliferation (BDUMP), due to bilateral round oval patches at the posterior pole and cardinal signs in retinal angiography. Malignancy screening was suggested, and pathological report from gastroscopy confirmed the primary lesion as gastric adenocarcinoma. The patient chose palliative care due to late stage and unresectable nature of the malignancy. Identifying BDUMP warrants further investigation of a primary malignancy. Our case provided evidence for the link between gastric adenocarcinoma and BDUMP.

中文翻译：

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诊断为双侧弥漫性葡萄膜黑色素细胞增生揭示原发性胃腺癌：一例报告

双边弥漫性葡萄膜黑素细胞增生（BDUMP）是一种极为罕见的副肿瘤综合征，据报道大多数病例是继发于女性泌尿生殖系统和男性肺部恶性肿瘤。我们报道了此例BDUMP患者，其原发性恶性肿瘤经胃镜检查和随后的病理学检查证实为胃腺癌。一名抱怨视力模糊的患者被怀疑是双侧弥漫性葡萄膜黑素细胞增生（BDUMP），这是由于后极处的双侧圆形椭圆形斑块和视网膜血管造影中的基本体征所致。建议进行恶性肿瘤筛查，胃镜检查的病理报告证实原发灶为胃腺癌。由于恶性肿瘤的晚期和不可切除的性质，患者选择了姑息治疗。确定BDUMP值得进一步研究原发性恶性肿瘤。