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Human anelloviruses: diverse, omnipresent and commensal members of the virome.
FEMS Microbiology Reviews ( IF 10.1 ) Pub Date : 2020-03-19 , DOI: 10.1093/femsre/fuaa007
Joanna Kaczorowska 1 , Lia van der Hoek 1
Affiliation  

Anelloviruses are small, single stranded circular DNA viruses. They are extremely diverse and have not been associated with any disease so far. Strikingly, these small entities infect most probably the complete human population, and there are no convincing examples demonstrating viral clearance from infected individuals. The main transmission could be via fecal-oral or airway route, as infections occur at an early age. However, due to the lack of an appropriate culture system, the virus–host interactions remain enigmatic. Anelloviruses are obviously mysterious viruses, and their impact on human life is not yet known, but, with no evidence of a disease association, a potential beneficial effect on human health should also be investigated.

中文翻译:

人类网膜病毒:病毒的多种多样,无所不在和共同的成员。

Anelloviruses是小的单链环状DNA病毒。它们极为多样,迄今为止尚未与任何疾病相关。令人惊讶的是,这些小实体很可能感染了整个人类,并且没有令人信服的例子表明感染者清除了病毒。主要的传播途径可能是通过粪口或气道传播,因为感染是在早期发生的。但是,由于缺乏合适的培养系统,病毒与宿主之间的相互作用仍然难以捉摸。Anelloviruss显然是神秘的病毒,尚不清楚它们对人类生活的影响,但是,在没有疾病相关证据的情况下,还应研究对人类健康的潜在有益影响。
更新日期:2020-03-19
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