当前位置: X-MOL 学术Neuroscience › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The Contribution of Motor Commands to the Perturbations Induced by Sensorimotor Conflicts in Fibromyalgia.
Neuroscience ( IF 2.9 ) Pub Date : 2020-03-19 , DOI: 10.1016/j.neuroscience.2020.03.017
Clémentine Brun 1 , Candida S McCabe 2 , Catherine Mercier 1
Affiliation  

Individuals with pain report higher sensory disturbances during sensorimotor conflicts compared to pain-free individuals. In the pain field, it is frequently assumed that disturbances arise from a discordance between sensory and efference copies (defined as sensory-motor conflict), while in the sensorimotor control field they are considered to result from the incongruence between sensory modalities (defined as sensory-sensory conflict). The general aim of this study was to disentangle the relative contribution of motor efferences and sensory afferences to the increased sensitivity to sensorimotor conflicts in individual with fibromyalgia (n = 20) compared to controls (n = 20). We assessed sensory and motor disturbances during sensory-sensory and sensory-motor conflicts using a robotized exoskeleton interfaced with a 2D virtual environment. There was a significant interaction between the group and the type of conflict (p = 0.03). Moreover, the increase in conflict sensitivity from sensory-sensory to sensory-motor conflicts in fibromyalgia was related to conflict-induced motor disturbances (r = 0.57; p < 0.01), but did not result from a poorer proprioception (r = 0.12; p = 0.61). Therefore, it appears that higher conflict sensitivity in fibromyalgia is mainly explained by a sensory-motor conflict rather by a sensory-sensory conflict. We suggest this arises due to a deficit in updating predicted sensory feedback rather than in selecting appropriate motor commands.

中文翻译:

运动命令对纤维肌痛中感觉运动冲突引起的摄动的贡献。

与无疼痛的人相比,有疼痛的人在感觉运动冲突期间报告较高的感觉障碍。在疼痛领域中,通常认为干扰是由感觉拷贝与感觉拷贝之间的不一致(定义为感觉运动冲突)引起的,而在感觉运动控制领域中,它们被认为是由于感觉模态之间的不一致(定义为感觉运动)引起的。 -感官冲突)。这项研究的总体目标是,与对照组(n = 20)相比,理清运动影响和感觉障碍对纤维肌痛患者(n = 20)对感觉运动冲突敏感性增加的相对贡献。我们使用与2D虚拟环境接口的机器人化外骨骼,在感觉-感觉和感觉-运动冲突期间评估了感觉和运动障碍。小组与冲突类型之间存在显着的相互作用(p = 0.03)。此外,纤维肌痛中从感觉到冲突到感觉-运动冲突的冲突敏感性增加与冲突引起的运动障碍有关(r = 0.57; p <0.01),但不是由于本体感觉差(r = 0.12; p = 0.61)。因此,看来纤维肌痛中较高的冲突敏感性主要是由感觉-运动冲突而不是由感觉-感觉冲突解释的。我们建议,这是由于更新预测的感官反馈而不是选择适当的运动命令方面的缺陷引起的。纤维肌痛中从感觉-感觉到感觉-运动冲突的冲突敏感性增加与冲突引起的运动障碍有关(r = 0.57; p <0.01),但并不是由于本体感觉较差(r = 0.12; p = 0.61) )。因此,看来纤维肌痛中较高的冲突敏感性主要是由感觉-运动冲突而不是由感觉-感觉冲突解释的。我们建议,这是由于更新预测的感官反馈而不是选择适当的运动命令方面的缺陷引起的。纤维肌痛中从感觉-感觉到感觉-运动冲突的冲突敏感性增加与冲突引起的运动障碍有关(r = 0.57; p <0.01),但并不是由于本体感觉较差(r = 0.12; p = 0.61) )。因此,看来纤维肌痛中较高的冲突敏感性主要是由感觉-运动冲突而不是由感觉-感觉冲突解释的。我们建议,这是由于更新预测的感官反馈而不是选择适当的运动命令方面的缺陷引起的。
更新日期:2020-03-19
down
wechat
bug