Au-Ag nanoparticle arrays were deposited on a flexible and surface-modified polydimethylsiloxane (PDMS) substrate for surface-enhanced Raman scattering (SERS). The surface of the PDMS substrate was modified to be a hydrophilic layer by nitrogen (N₂) atmospheric plasma treatment. When compared to the non-plasma-treated PDMS substrate, the contact angle of the plasma-treated PDMS substrate decreased from 115.4° to 32° to form the hydrophilic surface of the PDMS substrate. The uniform Au-Ag nanoparticle arrays were further deposited by thermal evaporation on the plasma-treated PDMS substrate that was evaluated by scanning electron microscopy (SEM). The results indicate that the Au-Ag@PDMS-N₂ substrate exhibited highly sensitive and reproducible SERS spectra of adenine (10⁻⁴ M) due to the homogeneous and narrow interparticle gap (~2 nm) between Au-Ag nanoparticles. Particularly, the SERS intensity of 2Au-6Ag@PDMS-N₂ substrate increased ~4 times under a bending angle of 5°. This indicated that the flexible behaviors of the PDMS-based SERS substrate can effectively manipulate the interparticle gap between Au-Ag nanoparticles by bending the SERS substrate. Therefore, the flexible and ultrasensitive SERS substrate fabricated by Au-Ag nanoparticles deposited on plasma-treated PDMS substrate provides enormous potential for practical applications in detecting biomolecules and environmental pollutants.

Au-Ag纳米颗粒阵列沉积在用于表面增强拉曼散射（SERS）的柔性和表面改性的聚二甲基硅氧烷（PDMS）基板上。通过氮气（N ₂）大气等离子体处理将PDMS基板的表面改性为亲水层。当与未等离子体处理的PDMS基板相比时，等离子体处理的PDMS基板的接触角从115.4°减小至32°以形成PDMS基板的亲水性表面。通过热蒸发将均匀的Au-Ag纳米颗粒阵列进一步沉积在经等离子体处理的PDMS衬底上，该PDMS衬底通过扫描电子显微镜（SEM）评估。该结果表明，金-银@ PDMS-N ₂基板表现出腺嘌呤高度敏感的和可再现的SERS光谱（10 ^-4 M）是由于Au-Ag纳米颗粒之间均匀且狭窄的颗粒间间隙（〜2 nm）。特别是，在5°的弯曲角度下，2Au-6Ag @ PDMS-N ₂衬底的SERS强度增加了约4倍。这表明基于PDMS的SERS基底的柔性行为可以通过弯曲SERS基底来有效地操纵Au-Ag纳米粒子之间的粒子间间隙。因此，由沉积在等离子体处理过的PDMS基板上的Au-Ag纳米粒子制成的柔性超灵敏SERS基板为检测生物分子和环境污染物的实际应用提供了巨大的潜力。