Frugal Innovation for Point-of-Care Diagnostics Controlling Outbreaks and Epidemics,ACS Biomaterials Science & Engineering

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Frugal Innovation for Point-of-Care Diagnostics Controlling Outbreaks and Epidemics
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2020-03-18 , DOI: 10.1021/acsbiomaterials.9b01712
Tobias Miesler ₁ , Christine Wimschneider ₂ , Alexander Brem _{3,

4} , Lorenz Meinel _{1,

5}

Affiliation

Today epidemics of infectious diseases occur more often and spread both faster and further due to globalization and changes in our lifestyle. One way to meet these biological threats are so-called “Frugal Innovations”, which focus on the development of affordable, rapid, and easy-to-use diagnostics with widespread use. In this context, point-of-care-tests (POCTs), performed at the patient’s bedside, reduce extensive waiting times and unnecessary treatments and enable effective containment measures. This Perspective covers advances in POCT diagnostics on the basis of frugal innovation characteristics that will enable a faster, less expensive, and more convenient reaction to upcoming epidemics. Established POCT systems on the health care market, as well as currently evolving technological advancements in that sector are discussed. Progress in POCT technology and insights on how to most effectively use them allows the handling of more patients in a shorter time frame and consequently improves clinical outcomes at lower cost.

中文翻译：

节俭创新的护理点控制爆发和流行

如今，由于全球化和生活方式的改变，传染病的流行更加频繁，并且传播得越来越快。应对这些生物威胁的一种方法就是所谓的“节俭创新”，它着眼于开发价格合理，快速且易于使用的诊断方法，并广泛使用。在这种情况下，在患者床边进行的即时检验（POCT）可以减少大量的等待时间和不必要的治疗，并可以采取有效的收容措施。该观点涵盖了基于节俭创新特征的POCT诊断方面的进展，这些特征将使人们能够对即将到来的流行病更快，更便宜，更方便地做出反应。讨论了在医疗保健市场上已建立的POCT系统，以及该领域当前正在发展的技术进步。

更新日期：2020-03-18

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