At present, there is no need and no sufficient evidence to support universal screening for vitamin D status. There are four categories of subjects in whom there is no requirement for screening, since a number of studies indicate beneficial effects of vitamin D supplementation; these are represented by children and adolescents, pregnant women, patients taking bone active drugs and subjects with documented hypovitaminosis D. In the remaining subjects, the utilization of adequate questionnaires will target with sufficient sensitivity and specificity those with hypovitaminosis D. These must be first supplemented and, at a later time, serum 25(OH)D assay should be requested to confirm attainment of sufficiency, independently of the threshold chosen. This strategy will cut costs deriving from both widespread use of vitamin D assays and vitamin D supplementation.

目前，没有必要也没有足够的证据来支持普遍筛查维生素D状况。无需筛查的对象有四类，因为许多研究表明补充维生素D具有有益作用。这些以儿童和青少年，孕妇，服用骨活性药物的患者以及有维生素D缺乏症的受试者为代表。在其余受试者中，使用足够的问卷将针对维生素D缺乏症的受试者具有足够的敏感性和特异性。这些必须首先补充并且在以后的时间，应该要求进行血清25（OH）D测定以确认是否达到足够的水平，而与选择的阈值无关。