AIM The aim of this systematic review and meta-analysis was to assess the effect of Ramadan focused education on clinical and metabolic parameters in patients with type 2 diabetes who fast during Ramadan. METHODS Literature search was done in PubMed, Embase (Ovid), and the Cochrane Library. Quality assessment was done using the ROBINS-I and Cochrane tools for risk of bias and analyses were performed using RevMan version 5.1. RESULTS From 770 records, 430 full text studies were assessed. After exclusions, the final quantitative analysis included 16 studies. Pre-Ramadan education was associated with a significant reduction in HbA1c (SMD -0.46, 95% CI -0.65 to -0.27P < 0.05) and LDL (SMD -0.09, 95% CI -0.13 to -0.04P < 0.05), an increase in TG (SMD 0.07, 95% CI -0.23 to 0.93P < 0.05) and weight (SMD 0.44, 95% CI 0.06 to 0.81P < 0.05) and no change in hypoglycemic events, BMI, TC, HDL or blood pressure (P > 0.05) during Ramadan. CONCLUSIONS This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. It also identifies a lack of head to head studies and limited observational studies with adequately assessed end-points.

中文翻译：

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斋月集中教育对2型糖尿病患者的影响：系统评价和荟萃分析。

目的本系统综述和荟萃分析的目的是评估斋月集中教育对斋月期间禁食的2型糖尿病患者的临床和代谢参数的影响。方法在PubMed，Embase（Ovid）和Cochrane图书馆中进行文献检索。使用ROBINS-I和Cochrane工具进行质量评估以评估存在偏倚的风险，并使用RevMan 5.1版进行分析。结果从770条记录中，评估了430条全文研究。排除后，最终的定量分析包括16个研究。斋月前的教育与HbA1c（SMD -0.46，95％CI -0.65至-0.27P <0.05）和LDL（SMD -0.09，95％CI -0.13至-0.04P <0.05）的显着降低有关。 TG（SMD 0.07，95％CI -0.23至0.93P <0.05）和体重增加（SMD 0.44，95％CI 0.06至0.81P <0）。05）斋月期间的降血糖事件，BMI，TC，HDL或血压无变化（P> 0.05）。结论这项系统的回顾和荟萃分析表明，斋月期间以糖尿病为重点的糖尿病教育导致HbA1c和LDL降低，但TG和体重增加。它也指出缺乏正面的研究和有限的观察性研究，并且没有足够的评估终点。