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Dopaminergic Control over the Tripartite Synapse.
Neuron ( IF 14.7 ) Pub Date : 2020-03-18 , DOI: 10.1016/j.neuron.2020.02.031
Jeroen P H Verharen 1 , Johannes W de Jong 1 , Stephan Lammel 1
Affiliation  

In this issue of Neuron, Corkrum et al. (2020) demonstrate an unexpected role for dopamine D1 receptors on astrocytes located in the nucleus accumbens, a key structure of the brain's reward system. Activation of these receptors mediates dopamine-evoked depression of excitatory synaptic transmission, which contributes to amphetamine's psychomotor effects.

中文翻译:

对三联突触的多巴胺能控制。

在本期《神经元》中,Corkrum等人。(2020)证明了伏隔核中星形胶质细胞上多巴胺D1受体的意外作用,这是大脑奖励系统的关键结构。这些受体的激活介导多巴胺引起的兴奋性突触传递抑制,这有助于苯丙胺的精神运动作用。
更新日期:2020-03-19
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