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Triacylglycerol Containing Medium-Chain Fatty Acids: Comparison of Human Milk and Infant Formulas on Lipolysis during In Vitro Digestion
Journal of Agricultural and Food Chemistry ( IF 6.1 ) Pub Date : 2020-03-30 , DOI: 10.1021/acs.jafc.9b07481
Tinglan Yuan 1, 2 , Ziwei Geng 1 , Xinyue Dai 1, 2 , Xinghe Zhang 1, 2 , Wei Wei 1, 2 , Xingguo Wang 1, 2 , Qingzhe Jin 1, 2
Affiliation  

Medium-chain triacylglycerol (MCT) is widely used in infant formulas (IFs) to provide medium-chain fatty acids (MCFAs) for infants with special fat absorption requirements. However, MCFAs naturally present in human milk are medium-and long-chain triacylglycerols (MLCTs). This study investigated the effect of triacylglycerol containing MCFAs (MLCT vs MCT) on lipolysis by comparison of human milk and IFs containing 0, 20, 30, and 55% of MCT (IF 1 to IF 4) using an in vitro digestion model. Rabbit gastric lipase showed an extent of digestion within the expected range, and was selected as the alternative to human gastric lipase. All IFs showed a lower lipolysis degree compared with human milk. There was no significant difference (p = 0.175) among IFs supplemented with MCT at the end of intestinal digestion. In addition, the digestion of IFs with different MCT contents led to different free fatty acid profiles, which may have health effects on infants.

中文翻译:

含中链脂肪酸的三酰基甘油:人乳和婴儿配方奶在体外消化过程中脂解作用的比较

中链三酰基甘油(MCT)被广泛用于婴儿配方食品(IF)中,以为有特殊脂肪吸收要求的婴儿提供中链脂肪酸(MCFA)。但是,人乳中天然存在的MCFA是中链和长链三酰基甘油(MLCT)。本实验研究含MCFAs(MLCT三酰基甘油的效果VS通过含有MCT的0,20,30,和55%(IF 1到IF 4)使用人乳的比较和IFS上脂肪分解MCT)体外消化模型。兔胃脂肪酶的消化程度在预期范围内,因此被选作人胃脂肪酶的替代品。与人乳相比,所有中频都显示出较低的脂解程度。没有显着差异(p在肠道消化结束时补充了MCT的IFs中,其= 0.175)。另外,具有不同MCT含量的IF的消化导致不同的游离脂肪酸谱,这可能对婴儿产生健康影响。
更新日期:2020-03-30
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