Herein, we reported a series of new 2‐(5‐methyl‐1‐aryl‐1H‐1,2,3‐triazol‐4‐yl)imidazo[1,2‐a]pyridines by using iodine and NH₄OAc in good yields. The structures of the titled compounds were characterized by the elemental analysis, ¹H NMR, ¹³C NMR, IR, and mass spectral analysis. All the titled compounds were screened for their in vitro antibacterial and antifungal activities by using streptomycin and Nystatin as standard drugs. The compounds 3k , 3l , 3g , and 3c exhibited potent activity against the tested bacterial strains and 3k , 3l , and 3c exhibited potent activity against the tested fungal strains than the reference drugs.

中文翻译：

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碘介导的新型咪唑并[1,2-a]吡啶衍生物的合成及其抗菌活性的评价

在这里，我们报道了一系列新的2-（5-甲基-1-芳基-1H-1,2,3-三唑-4-基）咪唑并[1,2-a]吡啶在碘和NH ₄ OAc中的应用。高产。通过元素分析，¹ H NMR，¹³ C NMR，IR和质谱分析表征标题化合物的结构。通过使用链霉素和制霉菌素作为标准药物，筛选了所有标题化合物的体外抗菌和抗真菌活性。化合物3k，3l，3g和3c对测试的细菌菌株和3k，3l表现出有效的活性和3c显示出比参考药物更强的抗测试真菌菌株的活性。