One of the emerging and recent strategies to combat cancer is application of natural bioactive compounds and phytochemicals. Carotenoids including lycopene, β-carotene, astaxanthin, crocin, β-cryptoxanthin, and lutein, are the main group of plant pigments which play important roles in the prevention and healing process of different diseases including cancer. The pharmacological use of carotenoid compounds is frequently limited by their low bioavailability and solubility as they are mainly lipophilic compounds. The present study focuses on the current data on formulation of different carotenoid nanodelivery systems for cancer therapy and a brief overview of the obtained results. Encapsulation of carotenoids within different nanocarriers is a remarkable approach and innovative strategy for the improvement of health-promoting features and particularly, cancer prevention/treatment roles of these compounds through enhancing their solubility, cellular uptake, membrane permeation, bioaccessibility, and stability. There is various nanocarrier for loading carotenoids including polymeric/biopolymeric, lipid-based, inorganic, and hybrid nanocarriers. Almost in all relevant studies, these nano delivery systems have shown promising results in improving the efficiency of carotenoids in cancer therapy.

对抗癌症的新兴战略之一是天然生物活性化合物和植物化学物质的应用。类胡萝卜素包括番茄红素，β-胡萝卜素，虾青素，番红花，β-隐黄质和叶黄素是主要的植物色素，在预防和治愈包括癌症在内的各种疾病中起着重要作用。由于类胡萝卜素化合物主要是亲脂性化合物，因此其生物利用度和溶解度低通常会限制其药理学用途。本研究的重点是用于癌症治疗的不同类胡萝卜素纳米递送系统配方的当前数据，以及所获得结果的简要概述。将类胡萝卜素包封在不同的纳米载体中是改善健康促进功能，尤其是通过增强化合物的溶解度，细胞吸收，膜渗透性，生物可及性和稳定性来改善这些化合物的癌症预防/治疗作用的杰出方法和创新策略。存在多种用于装载类胡萝卜素的纳米载体，包括聚合物/生物聚合物，基于脂质的，无机的和杂化的纳米载体。几乎在所有相关研究中，这些纳米递送系统在提高类胡萝卜素在癌症治疗中的效率方面均显示出令人鼓舞的结果。