Radio- and nano-chemistry of aqueous Ga(III) ions anchored onto graphene oxide-modified complexes,Nanoscale

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Radio- and nano-chemistry of aqueous Ga(III) ions anchored onto graphene oxide-modified complexes
Nanoscale ( IF 5.8 ) Pub Date : 2020/03/17 , DOI: 10.1039/c9nr10145d
S. Sarpaki _{1,

2,

3,

4} , F. Cortezon-Tamarit _{1,

2,

3,

4} , S. R. M. M. de Aguiar _{1,

2,

3,

4} , R. M. Exner _{1,

2,

3,

4} , D. Divall _{1,

2,

3,

4} , R. L. Arrowsmith _{1,

2,

3,

4} , H. Ge _{1,

2,

3,

4} , F. J. Palomares _{5,

6,

7,

8} , L. Carroll _{9,

10,

11,

12} , D. G. Calatayud _{7,

8,

13,

14} , S. J. Paisey _{4,

15,

16,

17,

18} , E. O. Aboagye _{19,

20,

21,

22,

23} , S. I. Pascu _{1,

2,

3,

4}

Affiliation

Department of Chemistry
University of Bath
BA2 7AY Bath
UK
Department of Nanostructures and Surfaces
Instituto de Ciencia de Materiales de Madrid – CSIC
Madrid, 28049
Spain
Department of Radiology & Radiological Science
Johns Hopkins
MD 21205
USA
Department of Electroceramics
Instituto de Cerámica y Vidrio – CSIC
Wales Research and Diagnostic PET Imaging Centre
School of Medicine
Cardiff University
Cardiff
Department of Surgery and Cancer
Faculty of Medicine
Commonwealth Building
Hammersmith Campus
Imperial College London

The gallium-68 radiolabelling of new functional graphene oxide composites is reported herein along with kinetic stability investigations of the radio-nanohybrids under different environments and insights into their surface characteristics by SEM and XPS. The present work highlights the potential of graphene oxides as nanocarriers for small molecules such as bis(thiosemicarbazonato) complexes to act as multifunctional platforms for rapid and effective radioimaging agent incorporation.

中文翻译：

固定在氧化石墨烯修饰的配合物上的Ga（III）水溶液的放射化学和纳米化学

本文报道了新型功能性氧化石墨烯复合材料的68镓放射性标记，以及在不同环境下对放射性纳米杂化物的动力学稳定性研究以及通过SEM和XPS对其表面特性的了解。本工作强调了石墨烯氧化物作为小分子（如双（硫代半碳氮杂萘）配合物）的纳米载体的纳米载体的潜力，以作为快速有效地掺入放射成像剂的多功能平台。

更新日期：2020-03-27

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