Sequence logos were introduced nearly 30 years ago as a human-readable format for representing consensus sequences, and they remain widely used. As new experimental and computational techniques have developed, logos have been extended: extra symbols represent covalent modifications to nucleotides, logos with multiple letters at each position illustrate models with multi-nucleotide features and symbols extending below the x-axis may represent a binding energy penalty for a residue or a negative weight output from a neural network. Web-based visualization tools for genomic data are increasingly taking advantage of modern web technology to offer dynamic, interactive figures to users, but support for sequence logos remains limited. Here, we present LogoJS, a Javascript package for rendering customizable, interactive, vector-graphic sequence logos and embedding them in web applications. LogoJS supports all the aforementioned logo extensions and is bundled with a companion web application for creating and sharing logos.

中文翻译：

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LogoJS：一个 Javascript 包，用于创建序列徽标并将其嵌入到 Web 应用程序中。


序列标识在近 30 年前被引入，作为一种人类可读的格式来表示共有序列，并且它们仍然被广泛使用。随着新的实验和计算技术的发展，标识得到了扩展：额外的符号代表对核苷酸的共价修饰，每个位置具有多个字母的标识说明具有多核苷酸特征的模型，并且延伸到x轴以下的符号可能代表结合能损失用于神经网络的残差或负权重输出。基于网络的基因组数据可视化工具越来越多地利用现代网络技术为用户提供动态、交互式图形，但对序列徽标的支持仍然有限。在这里，我们介绍 LogoJS，这是一个 Javascript 包，用于渲染可定制的、交互式的矢量图形序列徽标并将其嵌入到 Web 应用程序中。 LogoJS 支持所有上述徽标扩展，并与用于创建和共享徽标的配套 Web 应用程序捆绑在一起。