Compound crystallization is typically achieved from supersaturated solutions over time, through melting, or via sublimation. Here a new method to generate a single crystal of thioglucoside using a sub-10-fs pulse laser is presented. By focusing the laser pulse on a solution in a glass cell, a single crystal is deposited at the edge of the ceiling of the glass cell. This finding contrasts other non-photochemical laser-induced nucleation studies, which report that the nucleation sites are in the solution or at the air-solution interface, implying the present crystallization mechanism is different. Irradiation with the sub-10-fs laser pulse does not heat the solution but excites coherent molecular vibrations that evaporate the solution. Then, the evaporated solution is thought to be deposited on the glass wall. This method can form crystals even from unsaturated solutions, and the formed crystal does not include any solvent, allowing the formation of a pure crystal suitable for structural analysis, even from a minute amount of sample solution.

随着时间的推移，通过熔化或升华，化合物结晶通常是从过饱和溶液中实现的。这里介绍了一种使用亚 10-fs 脉冲激光生成硫葡糖苷单晶的新方法。通过将激光脉冲聚焦在玻璃池中的溶液上，单晶会沉积在玻璃池顶板的边缘。这一发现与其他非光化学激光诱导成核研究形成对比，这些研究报告成核位点在溶液中或在空气-溶液界面，这意味着目前的结晶机制是不同的。用亚 10-fs 激光脉冲照射不会加热溶液，但会激发使溶液蒸发的相干分子振动。然后，蒸发的溶液被认为沉积在玻璃壁上。