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Climacturia: a comprehensive review assessing pathophysiology, prevalence, impact, and treatment options regarding the “leak of pleasure”
International Journal of Impotence Research ( IF 2.8 ) Pub Date : 2020-03-17 , DOI: 10.1038/s41443-020-0257-1
Ioannis Mykoniatis 1, 2 , Koenraad van Renterghem 2, 3, 4 , Ioannis Sokolakis 5 , Georgios Hatzichristodoulou 5 , Maxime Sempels 1 , Robert Andrianne 1
Affiliation  

Aim of this review is to summarize and evaluate the current literature on the pathophysiology, prevalence, sociosexual impact, and potential treatment options of climacturia. Climacturia, defined as orgasm-associated urinary incontinence and characterized by great prevalence variability, ranging between 15.7 and 93% was, so far, a relatively neglected post-radical prostatectomy functional side-effect. Recent studies have shown that it can significantly impact the quality of life of couples after prostate cancer treatment. A knowledge gap characterizes the pathophysiologic pathways while treatment is based on empirically chosen treatment options (condom use, presexual intercourse urination) or on therapeutic modalities proposed by low-quality studies (pelvic floor muscle training, penile applied devices). Evidence regarding efficacy of surgical techniques (artificial urinary sphincter, male sling, or dual implantation of penile prosthesis with a sling) for climacturia treatment are limited but with an increasing trend of relevant published data in the last 5 years. The mini-jupette sling plus inflatable penile prosthesis placement is a promising surgical technique that has been studied in a multi-institutional cohort with encouraging results regarding climacturia, erectile dysfunction, and mild-incontinence control. However, future studies with longer follow-up and larger sample sizes are certainly needed to confirm the long-term safety and benefits of this intervention.



中文翻译:


更年期尿症:评估有关“快感泄漏”的病理生理学、患病率、影响和治疗方案的综合综述



本综述的目的是总结和评估有关更年期尿症的病理生理学、患病率、社会性影响和潜在治疗方案的现有文献。更年期尿症被定义为与性高潮相关的尿失禁,其患病率变异性很大,范围在 15.7% 至 93% 之间,迄今为止,是一种相对被忽视的根治性前列腺切除术后功能性副作用。最近的研究表明,它可以显着影响前列腺癌治疗后夫妇的生活质量。知识差距是病理生理学途径的特征,而治疗是基于经验选择的治疗方案(使用安全套、性交前排尿)或低质量研究提出的治疗方式(盆底肌肉训练、阴茎应用装置)。关于手术技术(人工尿道括约肌、男性吊带或带吊带的阴茎假体双重植入)治疗更年期尿症的疗效的证据有限,但在过去 5 年中相关发表的数据呈增加趋势。迷你朱佩特吊带加充气阴茎假体放置是一种有前途的手术技术,已在多机构队列中进行了研究,在更年期、勃起功能障碍和轻度失禁控制方面取得了令人鼓舞的结果。然而,未来肯定需要进行更长时间的随访和更大的样本量的研究来确认这种干预措施的长期安全性和益处。

更新日期:2020-04-24
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