Abstract After plasmochemical activation, chitosan-based coatings (containing silver or gold nanoparticles) were applied on nitinol (NiTi) alloy surface to study the effect of this functionalization on i) wettability, ii) corrosion resistance, iii) release of metal ions, and iv) cytotoxicity. Surface modification of nitinol based on (1) Ar/O2/NH3 plasma treatment and deposition of chitosan/AgNPs/vit.C coating (CS/AgNPs) or (2) Ar/O2/NH3 plasma treatment and deposition of chitosan/AuNPs coating (CS/AuNPs) resulted in decrease in water contact angle (enhanced hydrophilicity), increase in surface roughness parameters, improvement of corrosion resistance, and good biocompatibility (proved on human osteoblast-like cells in vitro), when compared to both unmodified NiTi and the chitosan layer itself. The proposed surface functionalization can potentially be a powerful and promising strategy for reducing pathogenic microorganism-associated infections without harmful effects towards mammalian cells, thus facilitating proper osseointegration.

中文翻译：

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壳聚糖/贵金属基涂层对 NiTi 合金等离子体化学活化表面的影响

摘要 等离子体化学活化后，将壳聚糖基涂层（含有银或金纳米粒子）应用于镍钛诺 (NiTi) 合金表面，以研究这种功能化对 i) 润湿性、ii) 耐腐蚀性、iii) 金属离子释放和iv) 细胞毒性。基于 (1) Ar/O2/NH3 等离子体处理和壳聚糖/AgNPs/vit.C 涂层 (CS/AgNPs) 或 (2) Ar/O2/NH3 等离子体处理和壳聚糖/AuNPs 涂层沉积的镍钛诺表面改性(CS/AuNPs) 导致水接触角减小（增强亲水性）、增加表面粗糙度参数、提高耐腐蚀性和良好的生物相容性（在体外人成骨细胞样细胞上证明），与未改性的 NiTi 和壳聚糖层本身。