Correlation between Surface Properties of Polystyrene and Polylactide Materials and Fibroblast and Osteoblast Cell Line Behavior: A Critical Overview of the Literature.,Biomacromolecules

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Correlation between Surface Properties of Polystyrene and Polylactide Materials and Fibroblast and Osteoblast Cell Line Behavior: A Critical Overview of the Literature.
Biomacromolecules ( IF 5.5 ) Pub Date : 2020-03-17 , DOI: 10.1021/acs.biomac.0c00214
Rémi G Tilkin _{1,

2} , Nicolas Régibeau _{1,

2} , Stéphanie D Lambert ₁ , Christian Grandfils ₂

Affiliation

Bone reconstruction remains an important challenge today in several clinical situations, notably regarding the control of the competition occurring during proliferation of osteoblasts and fibroblasts. Polystyrene and polylactide are reference materials in the biomedical field. Therefore, it could be expected from the literature that clear correlations have been already established between the behavior of fibroblasts or osteoblasts and the surface characteristics of these materials. After an extensive analysis of the literature, although general trends could be established, our critical review has highlighted the need to develop a more in-depth analysis of the surface properties of these materials. Moreover, the large variation noticed in the experimental conditions used for in vitro animal cell studies impairs comparison between studies. From our comprehensive review on this topic, we have suggested several parameters that would be valuable to standardize to integrate the data from the literature and improve our knowledge on the cell–material interactions.

中文翻译：

聚苯乙烯和聚丙交酯材料的表面性质与成纤维细胞和成骨细胞细胞系行为之间的相关性：文献的重要综述。

如今，在几种临床情况下，尤其是在控制成骨细胞和成纤维细胞增殖过程中发生的竞争方面，骨重建仍然是一项重要的挑战。聚苯乙烯和聚丙交酯是生物医学领域的参考材料。因此，可以从文献中预期，已经在成纤维细胞或成骨细胞的行为与这些材料的表面特性之间建立了明确的关联。在对文献进行了广泛的分析之后，尽管可以确定总体趋势，但我们的严格审查强调了需要对这些材料的表面性质进行更深入的分析。此外，在用于体外的实验条件中发现了很大的差异动物细胞研究削弱了研究之间的比较。通过对这一主题的全面回顾，我们提出了一些参数，这些参数对于标准化以整合文献数据和改善我们对细胞-材料相互作用的知识而言非常有价值。

更新日期：2020-03-17

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