Domino C–H Activation/Directing Group Migration/Alkyne Annulation: Unique Selectivity by d6-Cobalt(III) Catalysts,ACS Catalysis

当前位置： X-MOL 学术 › ACS Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Domino C–H Activation/Directing Group Migration/Alkyne Annulation: Unique Selectivity by d6-Cobalt(III) Catalysts
ACS Catalysis ( IF 11.3 ) Pub Date : 2020-03-26 , DOI: 10.1021/acscatal.9b05413
Cuiju Zhu ₁ , Rositha Kuniyil ₁ , Becky B. Jei ₁ , Lutz Ackermann ₁

Affiliation

Distinct selectivity control in Cp*Co^III-catalyzed domino C–H activation/pyridine directing group migration/alkyne annulation has been accomplished through the nucleophilicity of an organometallic cobalt intermediate with a d⁶ electron configuration. Detailed mechanistic studies provided compelling evidence for a facile C–H activation along with a favorable migration of the directing group for the Cp*Co^III catalysis, rather than the β-oxygen elimination observed for a (CO)₃Mn^I manifold.

中文翻译：

Domino C–H激活/定向组迁移/炔烃环化：d ^6-钴（III）催化剂的独特选择性

通过具有ad ⁶电子构型的有机金属钴中间体的亲核性，完成了Cp * Co ^III催化的多米诺骨牌CH-H活化/吡啶引导基团迁移/炔烃环化反应中的不同选择性控制。详细的机理研究提供了令人信服的证据，证明了C–H的活化很容易，并且Cp * Co ^III催化的导向基团有良好的迁移，而不是（CO）₃ Mn ^I歧管观察到的β-氧消除。

更新日期：2020-03-27

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11