Chitosan/collagen films were developed and characterized in order to assess the suitability of these films for biomedical applications. Hence, physicochemical, thermal, barrier and mechanical properties were analyzed and related to the film structure, which showed the prevalence of the triple helix of native collagen after the addition of chitosan. Furthermore, collagen fiber diameter changed from 3.9 ± 0.6 μm, for collagen films without chitosan, to 1.8 ± 0.5 μm, for collagen films with low molecular weight chitosan. These results suggested interactions between collagen and chitosan molecules, as observed by Fourier transform infrared (FTIR) analysis. Regarding film barrier properties, chitosan/collagen films showed a water vapor transmission rate around 1174 g m⁻² day⁻¹, suitable for biomedical applications such as wound healing. Additionally, biological tests confirmed that the chitosan/collagen films developed are suitable for biomedical applications.

壳聚糖/胶原蛋白薄膜的开发和表征是为了评估这些薄膜在生物医学应用中的适用性。因此，分析了其理化性质，热性质，阻隔性和机械性质，并与膜结构有关，显示了加入壳聚糖后天然胶原蛋白三螺旋的普遍性。此外，胶原纤维直径从无壳聚糖的胶原膜的3.9±0.6μm变为低分子量壳聚糖的胶原膜的1.8±0.5μm。这些结果表明胶原和壳聚糖分子之间的相互作用，如通过傅立叶变换红外（FTIR）分析所观察到的。关于薄膜阻隔性能，壳聚糖/胶原蛋白薄膜的水蒸气透过率约为1174 g m ^-2  day ^-1，适用于生物医学应用，例如伤口愈合。此外，生物学测试证实，开发的壳聚糖/胶原蛋白膜适用于生物医学应用。