Chemotherapy remains the main treatment option for patients with several tumor types. In this issue of Cancer Cell, Salvador-Barbero et al. demonstrate that treatment with CDK4/6 inhibitors after application of taxanes (or other chemotherapeutic compounds) strongly potentiates the anti-tumor effect due to repression of DNA repair machinery.

中文翻译：

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癌症治疗中的化学疗法和CDK4 / 6抑制：时间决定一切。

化学疗法仍然是几种肿瘤类型患者的主要治疗选择。在这一期的癌细胞中，Salvador-Barbero等人。证明在施用紫杉烷类化合物（或其他化学治疗化合物）后用CDK4 / 6抑制剂治疗会由于抑制DNA修复机制而强烈增强其抗肿瘤作用。