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Nordic treatment practices survey and consensus for treatment of eyelid sebaceous carcinoma
BMC Ophthalmology ( IF 1.7 ) Pub Date : 2020-03-16 , DOI: 10.1186/s12886-020-01367-3
Tiina Leivo , Johanna Sarmela , Maria Enckell-Aaltonen , Eva Dafgård Kopp , Caroline Schmitt , Peter B. Toft , Haraldur Sigurdsson , Marita Uusitalo

The purpose was to describe the Nordic treatment practices and to reach a Nordic consensus for the treatment of sebaceous eyelid carcinoma. The treatment practices data was collected by a questionnaire with 37 questions to the Nordic oculoplastic surgeons and analyzed. A PubMed MEDLINE database search was done to gather data on the published treatment practices and recommendations. A working group that consisted of in minimum one senior consultant from each leading Nordic University Eye Hospital was assigned. A structured interactive method was used to establish the consensus. Twenty-four doctors responded to the questionnaire. 23/24 (96%) of the respondents took a biopsy before surgery. Regional lymph node scanning was routinely done by 14/23 (61%) and a systemic screening of a metastatic disease by 13/23 (57%). 6/22 (27%) never took conjunctival mapping biopsies and 12/23 (52%) never screened for Muir- Torre. Respondents used Mohs surgery, frozen section or multi-stage excision with delayed closure, and 5–6 mm was the mostly preferred margin. Sentinel lymph node biopsy was a possible option for 9/22 (41%) and cryotherapy and Mitomycin C for 6/22 (27%) respondents. 50% of respondents considered radiation as a treatment option. 15/16 (94%) respondents always followed-up their patients, most for 5 years. Two thirds scanned regional lymph nodes during the follow-up. Consensus was reached for 18 statements representing three domains: preoperative work-up, treatment and follow-up. Treatment practices differ in between the five Nordic countries which have similar public health care systems. In the article the authors present a Nordic consensus for the treatment of eyelid sebaceous carcinoma.

中文翻译:

北欧眼睑皮脂腺癌治疗实践调查与共识

目的是描述北欧治疗方法,并就皮脂性眼睑癌的治疗达成北欧共识。通过向北欧眼部整形外科医生进行问卷调查,收集了37个问题的治疗方法数据并进行了分析。进行了PubMed MEDLINE数据库搜索,以收集有关已发布的治疗方法和建议的数据。分配了一个工作组,该工作组至少由每家领先的北欧大学眼科医院的一名高级顾问组成。使用结构化的交互式方法建立共识。二十四位医生回答了问卷。23/24(96%)的受访者在手术前进行了活检。14/23(61%)常规进行区域淋巴结扫描,而13/23(57%)进行全身性转移性疾病筛查。6/22(27%)从未进行过结膜标本活检,而12/23(52%)从未进行过Muir-Torre筛查。受访者使用Mohs手术,冷冻切片或多阶段切除和延迟闭合,最优选5-6 mm的切缘。前哨淋巴结活检是9/22(41%)的可能选择,而冷冻疗法和丝裂霉素C对于6/22(27%)的受访者是可能的选择。50%的受访者认为放射线是一种治疗选择。15/16(94%)的受访者始终对其患者进行随访,大部分随访时间为5年。在随访过程中,三分之二扫描了区域淋巴结。对于代表三个领域的18项声明达成了共识:术前检查,治疗和随访。在拥有相似公共卫生保健系统的五个北欧国家之间,治疗方法有所不同。
更新日期:2020-03-16
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