We report a nickel/NHC-catalyzed branched-selective α-crotylation of simple ketones using 1,3-butadiene as the alkylation agent. This reaction is regioselective and operated under pH and redox-neutral conditions. Water was used as the sole additive, which significantly accelerates the transformation.

中文翻译：

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pH和氧化还原中性条件下水加速镍催化1，酮与1,3-丁二烯的α-甲酰化

我们报道了使用1,3-丁二烯作为烷基化剂的镍/ NHC催化的简单酮的支链选择性α-丁酰化。该反应是区域选择性的，并且在pH和氧化还原中性条件下进行。水被用作唯一的添加剂，这极大地促进了转化。