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Delayed presentation, diagnosis, and psychosocial aspects of male breast cancer.
Cancer Medicine ( IF 4 ) Pub Date : 2020-03-13 , DOI: 10.1002/cam4.2953
Michael Co 1, 2, 3 , Andrea Lee 1, 3 , Ava Kwong 1, 2, 3, 4, 5
Affiliation  

INTRODUCTION Male breast cancer is uncommon, delay in seeking medical attention often results in late presentation and poor prognosis. METHODS Retrospective review of a prospectively maintained database was performed. Patients who were still having regular follow-up were contacted for telephone interview. RESULTS In this study, 56 male breast cancer patients were treated in our center from January 1998 to December 2018, accounting for 0.88% of all breast cancers treated during the same period of time. Median age of onset was 61 years old (Range: 33-95). In this study, 6 (10.7%) patients presented with distant metastasis at the time of diagnosis and received palliative systemic treatment only. And, 50 patients were surgically treated and all had mastectomy. Axillary dissection was performed in 36 (72%) patients, while sentinel node biopsy was performed in 14 (28%) patients. Median tumor size was 23 mm (2-100 mm). A Majority were diagnosed with invasive carcinoma (NOS), while 38 (67.8%) patients were node positive.Here 36 (64.3%) patients were alive at the time of the study, 31 (86.1%) patients responded to the telephone interview. More than 90% of our patients expressed various degrees of embarrassment at the time of breast symptom onset. Similarly, more than 90% of these patients experienced embarrassment while waiting in the breast center with predominant female patients. Most patients (N = 26) were not aware that breast cancer can occur in men prior to the diagnosis. Median duration from symptoms to the first medical consultation was 12.4 months (1-120 months). CONCLUSION Male breast cancer is rare and patients usually present late, Lack of knowledge, public education, and embarrassment are the important related factors.

中文翻译:

男性乳腺癌的延迟表现、诊断和社会心理方面。

引言 男性乳腺癌并不常见,延迟就医往往导致就诊晚和预后不良。方法 对前瞻性维护的数据库进行回顾性审查。联系仍在定期随访的患者进行电话采访。结果 本研究1998年1月至2018年12月在我中心收治的男性乳腺癌患者56例,占同期所有乳腺癌患者的0.88%。中位发病年龄为 61 岁(范围:33-95)。在这项研究中,6 名 (10.7%) 患者在诊断时出现远处转移,仅接受姑息性全身治疗。并且,50 名患者接受了手术治疗,并且都进行了乳房切除术。36 名 (72%) 患者进行了腋窝清扫术,同时对 14 名 (28%) 患者进行了前哨淋巴结活检。中位肿瘤大小为 23 毫米(2-100 毫米)。大多数被诊断为浸润性癌 (NOS),而 38 (67.8%) 名患者淋巴结阳性。在研究时有 36 (64.3%) 名患者存活,31 (86.1%) 名患者接受电话采访。超过 90% 的患者在乳房症状​​出现时表现出不同程度的尴尬。同样,这些患者中有 90% 以上在以女性患者为主的乳腺中心等候时感到尴尬。大多数患者(N = 26)在诊断前并不知道男性可能患乳腺癌。从症状到第一次就诊的中位时间为 12.4 个月(1-120 个月)。结论 男性乳腺癌罕见,患者通常出现较晚,缺乏知识,
更新日期:2020-03-13
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