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Desloratadine and loratadine use associated with improved melanoma survival
Allergy ( IF 12.6 ) Pub Date : 2020-04-16 , DOI: 10.1111/all.14273
Ildikó Fritz 1 , Philippe Wagner 1 , Matteo Bottai 2 , Hanna Eriksson 3, 4, 5 , Christian Ingvar 6 , Isabelle Krakowski 3, 7 , Kari Nielsen 8 , Håkan Olsson 1, 9
Affiliation  

As cancer, like allergy, can result from chronic inflammation, anti-inflammatory allergy medications are a particularly suitable starting point in the search for novel cancer therapeutics(1). Some H2 -antihistamines have shown promise in cancer therapy, but modern H1 -antihistamines have not been widely studied in this role, despite being ubiquitous, affordable, and safe, as well as having much lower toxicity than conventional chemotherapeutics.

中文翻译:

地氯雷他定和氯雷他定的使用与改善黑色素瘤存活率相关

由于癌症与过敏症一样,可由慢性炎症引起,因此抗炎过敏药物是寻找新型癌症疗法的特别合适的起点 (1)。一些 H2 - 抗组胺药已在癌症治疗中显示出前景,但现代 H1 - 抗组胺药在这一作用中尚未得到广泛研究,尽管它们无处不在、价格合理且安全,并且毒性比传统化疗药物低得多。
更新日期:2020-04-16
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